Book The Best Hotels in Great River Road for 2026 from CA $117 - Fully Refundable Options - Expedia

A historic downtown street with vintage buildings, a church steeple, and a prominent clock tower.

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Go beyond your typical stay in Great River Road

Pet friendly

Hot tub

Apartment

Pool

Apart hotel

Cottage

Family friendly

Waterpark

Cabin

Houseboat

Farm

Check prices for these dates

Tonight

Sep 23 - Sep 24

Tomorrow

Sep 24 - Sep 25

This weekend

Sep 25 - Sep 27

Next weekend

Our top choices for Great River Road hotels

An indoor swimming pool with a blue interior, surrounded by a seating area with blue cushions and wicker furniture.

A hotel room with a large bed, two bedside tables with lamps, a TV, a shower area, and a bathroom.

A dining area with multiple tables and chairs, a kitchen area with appliances, and a blue wall.

A reception area with a stone wall, wooden reception desk, and a herringbone patterned floor.

1. AmericInn by Wyndham Prairie du Chien

Prairie Du Chien

United States

Angela

CA $106

CA $117 total

includes taxes & fees

Oct 11 - Oct 12

A compact hotel room with a kitchenette, a sofa, a coffee table, and a bed.

A living room with two beige sofas, a fireplace, and a flat-screen TV mounted on a brick wall.

A large, two-story house with a front porch, surrounded by a grassy field and trees.

A garden with a central fountain, surrounded by a brick pathway and various plants.

2. Days Inn by Wyndham Lake Village

Lake Village

United States

Ronitta

CA $109

CA $122 total

includes taxes & fees

Oct 2 - Oct 3

A Fairfield by Marriott hotel with a modern design, featuring a covered entrance, multiple floors, and a landscaped area with trees and shrubs.

An indoor swimming pool with a stone wall, seating area, and large windows.

A hotel room with a large window, a TV, a desk, a chair, a sofa, and a lamp.

A modern living room with a stone accent wall, a sofa, a coffee table, and a chair.

3. Fairfield Inn & Suites by Marriott La Crosse Downtown

Historic Downtown La Crosse

United States

Paula

CA $142

CA $163 total

includes taxes & fees

Oct 4 - Oct 5

A rooftop terrace with wicker furniture, offering a city view.

A lobby with seating areas, a chandelier, and a large pillar.

A hotel room with a large window offering a view of the Gateway Arch and a modern building.

A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.

4. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

United States

Salvatore

CA $189

CA $222 total

includes taxes & fees

Oct 18 - Oct 19

An indoor pool area with a hot tub, seating, and a stone wall.

A conference room with a large table, six chairs, a flat-screen TV, and a patterned carpet.

A reception desk with a marble top, wooden paneling, and a sign indicating it's the Drury Inn.

5. Drury Plaza Hotel St. Louis Union Station

Downtown West

United States

Robert

CA $189

CA $225 total

includes taxes & fees

Sep 29 - Sep 30

An indoor swimming pool with a hot tub, lounge chairs, and a brick wall with artwork.

A hotel room with two beds, a desk, a TV, and a painting on the wall.

A multi-story hotel with a prominent sign for 'Pearl Tree Inn by O'Dell'.

6. Pear Tree Inn St. Louis Near Union Station

Downtown West

United States

Michael

CA $164

CA $192 total

includes taxes & fees

Sep 29 - Sep 30

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

7. Wingate by Wyndham St. Louis Airport

St. Ann

United States

Tessa

CA $131

CA $154 total

includes taxes & fees

Sep 29 - Sep 30

The Clayton Plaza Hotel sign with a stone wall and plants in front.

A hotel room with two beds, a desk, a chair, and a television.

A lobby with a chandelier, a round table with a floral arrangement, and a painting on the wall.

A large conference room with rows of tables and chairs, a podium, and a buffet table with plates and napkins.

8. Clayton Plaza Hotel & Extended Stay

Clayton

United States

Sivakumar

CA $134

CA $156 total

includes taxes & fees

Oct 4 - Oct 5

A cozy lounge area with leather sofas, a fireplace, and a bar counter.

A traditional building with a stone facade, large windows, and outdoor seating area with wicker furniture.

A modern building with a unique, curved roof structure.

An outdoor patio area with a pool, red umbrellas, and seating arrangements.

9. The Cheshire

Richmond Heights

United States

Matthew

CA $200

CA $237 total

includes taxes & fees

Sep 27 - Sep 28

A courtyard with outdoor seating, a central fountain, and a view of a tower.

The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

A hotel room with two beds, a desk, and a chair.

A spacious lobby with a bar area, seating arrangements, and a clock on the wall.

10. The Knight Center at Washington University

St. Louis

United States

Kenney

CA $214

CA $246 total

includes taxes & fees

Oct 6 - Oct 7

A large hotel with a prominent tower and multiple parking areas.

A lobby with a large screen displaying "Hollywood Casino" and "Wood Casino" signs, multiple chandeliers, and a polished floor.

A crowded indoor space with a chandelier, brick walls, and tables where people are seated and standing.

A spacious lobby with a patterned carpet, a reception desk, and a seating area with a sofa and chairs.

11. Hollywood Casino & Hotel St. Louis

Riverport

United States

Nicole

CA $117

CA $178 total

includes taxes & fees

Oct 19 - Oct 20

An indoor swimming pool with a curved design, surrounded by palm trees and a white pool ladder.

A modern interior with a fireplace, a green armchair, and a patterned rug.

A modern hotel lobby with a reception desk, a digital information kiosk, and a patterned floor.

A modern hotel with a prominent neon sign, multiple floors, and a well-maintained lawn area.

12. Treasure Island Resort & Casino

Welch

United States

Gina

CA $110

CA $138 total

includes taxes & fees

Sep 24 - Sep 25

An indoor swimming pool with a water slide, lounge chairs, and large windows.

A kitchen with white tiled backsplash, wooden cabinets, and a countertop with waffle irons, a grill, and bowls of food.

A living room with a stone fireplace, a sofa set, a wooden coffee table, and a bookshelf.

A Country Inn & Suites with a covered entrance, outdoor seating area, and a parking lot.

13. Country Inn & Suites by Radisson, Galena, IL

Galena

United States

Jesus

CA $138

CA $153 total

includes taxes & fees

Sep 29 - Sep 30

A hotel room with a large bed, a desk with a computer, a television, and a bathtub.

A bar area with a long counter, multiple bottles, glasses, and a few chairs.

A hotel room with a sofa, armchair, small table, TV, dresser, and a bathtub.

A multi-story hotel with a covered entrance and a sign indicating it is part of the Oak Hill Inn & Suites.

14. Oak Hill Inn & Suites

Canton

United States

Denny

CA $142

CA $162 total

includes taxes & fees

Sep 27 - Sep 28

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A hotel room with a bed, two armchairs, a sofa, a small table, and a nightstand.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A hotel reception area with a counter, seating, and a staircase.

15. Drury Inn & Suites St. Louis Airport

Edmundson

United States

Taneka

CA $161

CA $189 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

16. Pear Tree Inn St. Louis Airport

St. Ann

United States

Monica

CA $126

CA $149 total

includes taxes & fees

Sep 28 - Sep 29

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

17. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

United States

Sandra

CA $140

CA $158 total

includes taxes & fees

Sep 28 - Sep 29

A person underwater in a pool.

A hotel lobby with seating areas, a reception desk, and a view of the outdoors.

A gym with exercise equipment and a person lifting weights.

A hotel entrance with a covered walkway, cars parked outside, and a clear sky.

18. Gundersen Hotel & Suites

Powell-Poage-Hamilton

United States

Jean

CA $143

CA $165 total

includes taxes & fees

Sep 27 - Sep 28

A multi-story hotel with a modern design, featuring a covered entrance and a landscaped area with potted plants.

A hotel room with a large bed, a desk, a chair, and a view of the outdoors.

A hotel room with a sofa, armchairs, a coffee table, and a large painting on the wall.

19. Riverwalk Casino Hotel

Vicksburg

United States

Linda

CA $125

CA $138 total

includes taxes & fees

Oct 6 - Oct 7

An indoor swimming pool with a stone wall, wooden beams, and a stone fireplace.

A spacious lobby with a stone fireplace, wooden ceiling, and a patterned carpet.

A cozy living room with a stone fireplace, leather sofas, and a coffee table.

A log cabin-style room with a stone fireplace, a television, a sofa, a bed, and a bathtub.

20. Stoney Creek Hotel La Crosse - Onalaska

Onalaska

United States

Michael

CA $145

CA $164 total

includes taxes & fees

Sep 27 - Sep 28

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Learn more about Great River Road

Discover things to see and do in Great River Road as you venture to popular sights like Canal Street.

See all hotels in Great River Road

A historic downtown street with vintage buildings, a church steeple, and a prominent clock tower.

Top Great River Road Hotel Reviews

Reel Paradise at Shore Slough

Reel Paradise at Shore Slough

10/10 Excellent

"We had a great stay and the place was clean and in a great location to downtown Lansing!"

AmericInn by Wyndham Prairie du Chien

AmericInn by Wyndham Prairie du Chien

10/10 Excellent

"We only stayed one night. But definitely enjoyed our stay it was quiet, and clean"

Les Carillons - Arts District Gem
Large Groups Welcome! Pool! Elevator!

Les Carillons - Arts District Gem Large Groups Welcome! Pool! Elevator!

10/10 Excellent

"Lee Ann is a wonderful host, and my group and I thoroughly enjoyed our stay. The location is ideal with local bars and restaurants in the immediate vicinity, but it's still walkable to Bourbon St and the Superdome. The house is spacious and amenities like towels and shampoo were plentiful. Pool access was easy and the leftover sunscreen and festive hats were much appreciated. We would absolutely stay here again."

More cheap stays in Great River Road

Motel 6 Los Angeles, CA - Los Angeles - LAX

Motel 6 Los Angeles, CA - Los Angeles - LAX

5101 W Century Blvd Inglewood CA

CA $103

CA $119 total

Oct 14 - Oct 15

includes taxes & fees

Ontario Airport Inn

Ontario Airport Inn

1801 E G St Ontario CA

CA $118

CA $136 total

Oct 22 - Oct 23

includes taxes & fees

Best Western Plus Ruby's Inn

Best Western Plus Ruby's Inn

26 South Main Street Bryce Canyon UT

CA $119

CA $145 total

Oct 18 - Oct 19

includes taxes & fees

Motel 6 Anaheim Maingate

Motel 6 Anaheim Maingate

Anaheim CA

CA $132

CA $154 total

Sep 27 - Sep 28

includes taxes & fees

8/10 Very good! (6,861 reviews)

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

715 1st St N Jacksonville Beach FL

CA $209

CA $238 total

Sep 28 - Sep 29

includes taxes & fees

Hampton Inn Chicago Downtown/Magnificent Mile

Hampton Inn Chicago Downtown/Magnificent Mile

160 E Huron Street Chicago IL

CA $274

CA $326 total

Sep 27 - Sep 28

includes taxes & fees

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